Author Topic: KERBOOM I found something  (Read 2453 times)

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Offline kelee877

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KERBOOM I found something
« on: November 13, 2014, 06:25:37 AM »
ok it may not be a lot but it is something..Today they are going to start giving plasma and blood to infected Ebola patients and I wanted to read about past studies...and after reading about 40 pages of mumbo jumbo..look what I found..please keep this in this section as it is an important ground zero piece of information and I make look in to this deeper




Our data suggest that the Sierra Leone outbreak stemmed from the introduction of two genetically distinct viruses from Guinea around the same time. Samples from 12 of the first EVD patients in Sierra Leone, all believed to have attended the funeral of an EVD case from Guinea, fall into two distinct clusters (clusters 1 and 2) ([/size]Fig. 4A[/color][/size]and fig. S8). Molecular dating places the divergence of these two lineages in late April ([/color][/size]Fig. 3B[/font][/size][/color][/size]), predating their co-appearance in Sierra Leone in late May ([/color][/size]Fig. 4B[/font][/size][/color][/size]); this finding suggests that the funeral attendees were most likely infected by two lineages then circulating in Guinea, possibly at the funeral (fig. S9). All subsequent diversity in Sierra Leone accumulated on the background of those two lineages ([/color][/size]Fig. 4A[/font][/size][/color][/size]), consistent with epidemiological information from tracing contacts.[/color][/size][/color][/size][/color][/size]http://www.sciencemag.org/content/345/6202/1369.full[/color][/size]I still have to read further in the ,but stopped to post this somewhere were I knew I could find it again..thank you[/color]
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Offline kelee877

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Re: KERBOOM I found something
« Reply #1 on: November 13, 2014, 06:57:02 AM »
note to myself..


ground zero was said to have been a 2 year old girl that began all of this...when did this funeral take place in the above..all indications point to June of 2014


I can find no information so far on what 2 strains these are


and if I check charts it looks like the mutation of these 2 strains at this funeral where the beginning of the spike in cases occuring in and around April to June


more information is required to form what could be the monster in the closest and again the WHO and CDC have no idea what they are dealing with


could the news black out be because another mutation of higher consequences has occured
« Last Edit: November 13, 2014, 07:10:37 AM by kelee877 »
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Offline kelee877

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Re: KERBOOM I found something
« Reply #2 on: November 13, 2014, 06:58:57 AM »
another tidbit of information I would like to follow up on




Ebola Virus Patented by US Government in October 2009: “Invention Related to Novel Species of Human Ebola (hEbola) virus”
http://www.globalresearch.ca/the-ebola-virus-was-patented-by-the-us-government-in-october-2009-invention-related-novel-species-of-human-ebola-hebola-virus/5403142

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Offline kelee877

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Re: KERBOOM I found something
« Reply #3 on: November 13, 2014, 07:15:12 AM »
heading to work will read more of this one when I get home


http://wiki.eclipse.org/images/1/18/Deep_Dive_Oct_15_Operon_Labs_v1.pdf






? If they have patient A who is multi clad and give them blood plasma from patient B who is only single clad...what will happen especially since it takes numerous days to even test for Ebola..and even longer to do gene sequencing?
« Last Edit: November 13, 2014, 07:24:27 AM by kelee877 »
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Offline NObshere

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Re: KERBOOM I found something
« Reply #4 on: November 13, 2014, 07:43:32 AM »
Thanks for your insights and research K
Never stop...

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Offline kelee877

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Re: KERBOOM I found something
« Reply #5 on: November 13, 2014, 01:51:41 PM »
Thanks for your insights and research K


Thank You..it is still awork in progress, but for all the news I have read about Ebola, I have never seen any mention of their being multi viurs' in one person...home from work need a bit to eat and I left all my pages open to do a follow up
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Offline kelee877

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Re: KERBOOM I found something
« Reply #6 on: November 14, 2014, 09:47:00 AM »
The Gire et al. paper examines Ebola sequences from Sierra Leone during May and June identifying 55 new mutations that have occurred during the West African outbreak. Most of these mutations are shared by just one or a small handful of cases, but there is a particular mutation at genomic site 10218 that first appears at the beginning of June that distinguishes two major clades of virus (shown in blue and red below).


We use this method to compare growth rates in clade 2 and clade 3 viruses, finding a significantly higher growth rate in clade 3 viruses. This suggests that clade 3 viruses spread more rapidly than clade 2 viruses during the May/June study period

more at link

http://bedford.io/blog/
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Offline Henry

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Re: KERBOOM I found something
« Reply #7 on: November 14, 2014, 10:30:45 AM »
No offence intended , but I like to know why are you so obsessed with ebola  issue ?
Some people decided it would be nice to loose few people in Africa and experiment with the virus and it is also good story for the media.
Henry
 

Offline kelee877

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Re: KERBOOM I found something
« Reply #8 on: November 14, 2014, 11:14:32 AM »
No offence intended , but I like to know why are you so obsessed with ebola  issue ?
Some people decided it would be nice to loose few people in Africa and experiment with the virus and it is also good story for the media.
Henry


Henry I for years been a pandemic watcher....when I did the Just Measures Radio show that was my specialty was to follow and find information about possible pandemics...


I do not find it an obession, I like to be informed as do millions of others...if this has mutated and becomes airborne then we are all in a heap of trouble..and I for one am a survivolist and would like to know how to survive a major pandemic..




by bringng together information on a specific virus we may know how better to protect ourselves and our loved ones...if you think the governement will be there for you no way they will be in their own bunkers protecting their own
« Last Edit: November 14, 2014, 12:03:18 PM by kelee877 »
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Offline kelee877

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Re: KERBOOM I found something
« Reply #9 on: November 14, 2014, 11:49:59 AM »
I gave a brief reply to the above question and then went off to grab a bite to eat and take some more tylenol complete..night shift today




any mutation or viriant in a virus can be a global game changer...there was a lot huff on the news about Ebola and then it just went away..the news not Ebola


I for one do not trust WHO or the CDC they have never been transparent with information...so I look for my own..and sometimes to find out about the future we have to jump back to the past...no where on the news did we see that 2 seperate virus' had come together...as labeled in the charts at the first link they named them SL1 and SL2 that have come together and now we have SL3 and when the 2 seperate virus' combined we saw a major spike in cases and deaths, including 6 of the research team doing this study...yes level 4,complete PPE special equipment and 6 of them died from Ebola...


The one I posted today gives us the position of the mutation and I have been searching in past studies how this will change the virus..will it be more deadly or airborne,but since little is known about Ebola virus there is no further information to date...it is hard to study this virus as most that have done the research somehow come in contact and die or they do not continue


Other things I have found out in this research is that the rapid tests they are using are no longer working, the Ebola virus has changed and the test give a false/ negative result, this changes the numbers in a huge way..


bottom line for me is if this hits Canada then what is the best way to protect ourselves, the best preps to bring in at this time while they are available..should be bug out deeper or SIP...having this information now is imperative, before it disappears or is no longer available


In conclusion of the above posts of information I have come to conclusion that not enough study has been done the Ebola virus' and that no one knows how and where or especially when..more research and genetic sequencing in real time is needed to see if the virus has progressed and how the mutations are effecting its strength and transmission...


« Last Edit: November 14, 2014, 12:03:55 PM by kelee877 »
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Offline kelee877

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Re: KERBOOM I found something
« Reply #10 on: November 14, 2014, 12:04:52 PM »
here is something that explains what I am trying to say above





So what exactly do these 99 Ebola virus genomes reveal?



“The first thing we wanted to answer concretely was: Where did this (outbreak) come from?” said lead author Stephen Gire, a research scientist at Harvard University and the Broad Institute in Cambridge, Mass. “We wanted to see how each of these viruses we sequenced were related to each other and how they were related to past outbreaks.”



He and his colleagues found that the Ebola “lineages” in Sierra Leone could be traced back to the first outbreak ever recorded, which occurred in 1976 in the Democratic Republic of Congo, then called Zaire. About 10 years ago, however, the virus migrated from Central Africa to West Africa, perhaps through the animal “reservoir” for Ebola, believed to be the fruit bat.



The virus was not recognized in West Africa until March of this year, however, when the first case was confirmed in Guinea. Gire said the West African epidemic likely began after a single zoonotic event — in other words, transmission of the virus from an animal to a person. As with all Ebola outbreaks in the past, this one began with “a very strange introduction of a very strange virus into the human population,” Kuhn said. “Unfortunately, this time it led to a really big outbreak.”
In Sierra Leone, the virus appears to have entered the country through a traditional healer who died after treating patients in Guinea. At least 14 people attending her funeral contracted the virus, according to the paper.



What Gire found interesting, however, was that funeral attendees caught two different lineages of the Ebola virus. While the traditional healer may have been infected with both lineages, it is also possible that another person at the funeral was also infected and gave the virus to other attendees.
But one of those lineages quickly fizzled out, and soon after, the other one also faded into the background.
“About a week later or so, we see yet another lineage pop up,” Gire said. “Then that one rises to chief dominance within the population ... it’s really interesting to be able to map these out and use these mutations that the virus accumulates over time, to really sort of tease out transmission.”
Gire said his study shows that more than 300 mutations have occurred since Ebola began infecting people in Sierra Leone. Every time a virus passes from one person to another, it is likely some mutations will occur, though not all of them will be passed down.

What researchers worry about, however, are mutations that could help the virus become more infectious. The study’s authors pinpointed eight specific mutations on a section of the genome thought likely to be crucial to the virus’ survival. Gire said only future studies can draw conclusions on what these mutations mean — and speculating at this point would be irresponsible, Kuhn said — but it underscores the urgency of stopping this outbreak quickly.



“The biggest takeaway from this is that as time progresses from this outbreak, the virus is accumulating mutations,” Gire said. “You roll the dice more often, the more likely you’re going to hit something that matters.”

Gire said his paper’s findings could help determine whether current diagnostic tests being used in West Africa are working as well as they should. If the viruses circulating are mutating, then the current tests could be missing cases and generating false negatives. He also hopes these findings will be used by researchers trying to develop potential vaccines and therapies; according to Gire, San Diego researchers behind the Zmapp “serum” have already used their genetic sequences to re-evaluate their drug.

http://www.thestar.com/news/world/2014/08/28/dna_sequences_reveal_ebolas_spread_and_mutations.html
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Offline kelee877

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Re: KERBOOM I found something
« Reply #11 on: November 16, 2014, 07:48:57 AM »
Salia came down with symptoms of Ebola on 6 November but test results were negative for the deadly virus. He was tested again on Monday, and he tested positive. Salia is in stable condition at an Ebola treatment center in Freetown. It wasn’t clear whether he had been involved in the care of Ebola patients.
[/size][/color]
[/size]http://www.theguardian.com/world/2014/nov/14/doctor-with-ebola-being-brought-to-us[/color]
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